Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

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Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

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Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

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CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience

CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students

CBB Operator Working in the Lab

55 +

Associated UI Faculty

Microbial Manufacturing Services

As a microbial manufacturing & bioprocessing facility, our diverse team at the CBB specializes in cGMP and non-cGMP production of protein products for various business, commercial, and research purposes. We have years of experience in developing bioprocesses for scaling up fermentation & protein purification (including difficult to purified inclusion bodies), cGMP manufacturing, cell banking, instrumentation, and more. 

All critical equipment within the facility passed Factory Acceptance Tests (FAT), Installation Qualification (IQ), and Operational Qualification (OQ). This facility is open for audit by clients. 

With many successful campaigns over the years, the CBB has become a trusted partner for our local & international clients alike.

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We have worked with clients ranging from large pharmaceutical companies to biotech startups of all sizes to virtual companies, academic research labs, and governmental agencies. Our facility produces protein-based products for all sorts of purposes, including Phase-1 clinical trials. The quality of all manufactured products are ensured by our dedicated QA/QC team. 

Client Request Form
CBB Operator Working in the Lab

Non-cGMP Facility

Our non-cGMP Facility is fully equipped with advanced technologies & instruments to provide both upstream & downstream process development services to our clients, from strain development to large scale manufacturing. All projects are carried out by full-time staff with years of experience in research & process development. 

CBB Operator Working in the Lab

cGMP Facility

The cGMP Manufacturing Facility at CBB is capable of producing protein products for Phase-1 clinical trials. This cGMP Manufacturing Facility and the Non-cGMP Facility share similar equipment, allowing for efficient process transfer between the two facilities. Our facility strictly follows the 2008 FDA guidance for cGMP manufacturing of materials for Phase-1 investigational drugs. 

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

Educational & Training Opportunities

Every year, the CBB awards multiple fellowships to predoctoral student applicants to support their graduate research. In addition to our own CBB fellowship program, the CBB also administers NIH fellowships. 

Both NIH and CBB fellowships are designed to promote training focusing on the applications of biological & physical sciences to conduct interdisciplinary research in all domains of biotechnology. 

Learn More About Our Fellowships

Most of our fellows have successfully entered the biotech job market right after graduation because they not only graduated with multiple journal publications, but also with industrial internship experience. 

Fellowship Requirements

Supportive Faculty Trainers

Our fellows are students working in a CBB-associated faculty's laboratory at The University of Iowa. Faculty help students obtain internships, build their work portfolios, and prepare job application materials. 

Predoctoral graduate students are encouraged to discuss with their major advisors as soon as possible regarding the application process. Students in their 1st and 2nd year are given priority.

Supporting Fellows Beyond Graduation

Once a CBB fellow, always a CBB fellow-From academic to personal to professional development, the CBB & our committed faculty provide continuous guidance & mentorship to our fellows even after their graduation.

 

Participating Departments

"Center of Biocatalysis and Bioprocessing was very generous to award to me a 2-year Pre-Doctoral Fellowship in biotechnology for my PhD at UIOWA. Furthermore, I had a great opportunity of visit CBB facility and learn about protein purification services for Phase 1 clinical trial and downstream purification and bioprocessing."

Meet Some of Our Associated Faculty

Office of VP for Research Events

BMindful Holy Days: Passover (Judaism) promotional image

BMindful Holy Days: Passover (Judaism)

Monday, April 22 7:55pm to Tuesday, April 30, 2024 8:04pm
University of Iowa Division of Diversity, Equity, and Inclusion
BMindful is an initiative that seeks to meet the needs of diverse communities by providing event and conference planners with the dates of holy days of major religious faiths for five years into the future. By providing these dates in advance, BMindful seeks to help planners avoid those dates when scheduling events. BMindful does not include all religious holy days. It focuses on three major holy days for each faith—days when faith members may choose not to go to work or send their children to...
Iowa Archeological Society Annual Spring Meeting in Marquette, IA promotional image

Iowa Archeological Society Annual Spring Meeting in Marquette, IA

Saturday, April 27, 2024 8:00am
Driftless Area Wetlands Centre
Save the date for April 27, 2024, for the Iowa Archeological Society annual spring meeting! This year’s events will take place in northeast Iowa. We will hold morning presentations at the Driftless Area Wetlands Centre in Marquette, Iowa. IAS is partnering with Effigy Mounds National Monument for an afternoon field trip—stay tuned for details!

College of Medicine Events

Learn to Crochet Microbes!

Friday, March 1, 2024 4:00pm to Friday, February 28, 2025 5:00pm
Eckstein Medical Research Building
Learn to Crochet Microbes!   Bring your own yarn and needles if you have them! Contact: theresa-ho@uiowa.edu

Learn to Crochet Microbes!

Friday, March 8, 2024 4:00pm to Friday, March 7, 2025 5:00pm
Eckstein Medical Research Building
Learn to Crochet Microbes!   Bring your own yarn and needles if you have them! Contact: theresa-ho@uiowa.edu

College of Pharmacy Events

Kappa Psi Adopt-A-Highway Philanthropy Event promotional image

Kappa Psi Adopt-A-Highway Philanthropy Event

Sunday, April 28, 2024 9:30am to 11:30am
College of Pharmacy student members of Kappa Psi will be picking up trash along its adopted highway location, a two-mile stretch on Hwy 1 North of Iowa City. Pharmacy students can sign up to help here.
College of Pharmacy PSET Graduate Student Thesis Seminar: Neha Paranjape promotional image

College of Pharmacy PSET Graduate Student Thesis Seminar: Neha Paranjape

Monday, April 29, 2024 9:00am
College of Pharmacy Building
The Department of Pharmaceutical Sciences and Experimental Therapeutics in the College of Pharmacy will host a thesis seminar presented by Human Toxicology PhD candidate Neha Paranjape. Seminar Title: “Astrocytes as Targets of Lower Chlorinated Biphenyls” All are welcome to attend.