Aaron Ver Heul

DEPT: Biochemistry/Medicine        
YEAR OF GRAD STUDY: 2005-2013 (PhD 2007-2012)

MENTOR(S): Subramanian Ramaswamy and Robert Piper                                    
SOURCE(S) OF SUPPORT_ MSTP T32, Center for Biocatalysis and Bioprocessing grant

EDUCATION:
Iowa State University                         B.S.                                         2004                                       Biochemistry

HONORS:

TEACHING EXPERIENCE:
TA for 1) Experimental Biochemistry (catalog #99-140), 2) Biophysical Chemistry I (catalog #99-241).

RESEARCH EXPERIENCE (prior to entering program):
Investigations of catalytic mechanisms and synthesis of novel compounds by enzymes in the purine nucleotide biosynthesis pathway with Dr. Richard Honzatko at Iowa State

CURRENT RESEARCH ACTIVITIES (brief description):
Currently a clinical fellow and not involved in any basic science research. Will be back in the lab July, 2016.

POSTDOCTORAL TRAINING APPLIED FOR, UNDERWAY, OR COMPLETED:
Wash U in St Louis PSTP    Medicine/Immunology    

APPLICATION(S) FOR FUNDING (BUT THIS PROGRAM): None so far

PUBLICATIONS: 
1)            Ver Heul, A. M., Fowler, C. A., Ramaswamy, S., and Piper, R. C. (2013) Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2. Journal of Biological Chemistry 288, 6890–6902
2)            Ver Heul, A. M., Gakhar, L., Piper, R. C. and Ramaswamy, S. (2014) Crystal Structure of a Complex of NOD1 CARD and Ubiquitin. PLOS ONE, 9(8): e104017