YEAR OF GRAD STUDY: 2005-2013 (PhD 2007-2012)
MENTOR(S): Subramanian Ramaswamy and Robert Piper
SOURCE(S) OF SUPPORT_ MSTP T32, Center for Biocatalysis and Bioprocessing grant
Iowa State University B.S. 2004 Biochemistry
TA for 1) Experimental Biochemistry (catalog #99-140), 2) Biophysical Chemistry I (catalog #99-241).
RESEARCH EXPERIENCE (prior to entering program):
Investigations of catalytic mechanisms and synthesis of novel compounds by enzymes in the purine nucleotide biosynthesis pathway with Dr. Richard Honzatko at Iowa State
CURRENT RESEARCH ACTIVITIES (brief description):
Currently a clinical fellow and not involved in any basic science research. Will be back in the lab July, 2016.
POSTDOCTORAL TRAINING APPLIED FOR, UNDERWAY, OR COMPLETED:
Wash U in St Louis PSTP Medicine/Immunology
APPLICATION(S) FOR FUNDING (BUT THIS PROGRAM): None so far
1) Ver Heul, A. M., Fowler, C. A., Ramaswamy, S., and Piper, R. C. (2013) Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2. Journal of Biological Chemistry 288, 6890–6902
2) Ver Heul, A. M., Gakhar, L., Piper, R. C. and Ramaswamy, S. (2014) Crystal Structure of a Complex of NOD1 CARD and Ubiquitin. PLOS ONE, 9(8): e104017