Fellow's Publications

Fellowship acknowledgement

All fellow's publications supported by the fellowship should have the following acknowledgementFinancial support for student fellowship to xxx is acknowledged from the Center for Biocatalysis and Bioprocessing at the University of Iowa and the NIH Predoctoral Training Program in Biotechnology (grant number T32-GM008365)

Harrison Fuchs (Fellowship 2018-2019)

*Parida, M., Nilson, K.A., Ball, C.B., Fuchs, H.A., Lawson, C.K., Luse, D.S., Meier, J.L., Price, D.H. (2019) Nucleotide Resolution Comparison of Transcription of Human Cytomegalovirus and Host Genomes Reveals Universal Use of RNA Polymerase II Elongation Control Driven by Dissimilar Core Promoter Elements. mBio. 10:e02047-18. https://doi.org/10.1128/mBio.02047-18


Ilya Gurevic (Fellowship 2015-2017)

*Islam, Zahidul^; Gurevic, Ilya^; Strutzenberg, Timothy; Ghosh, Ananda; Iqbal, Tasnia; Kohen, Amnon. “Bacterial versus human thymidylate synthase: Kinetics and functionality.” PLoS ONE. 2018, 13 (5), e0196506. (^authors contributed equally)

*Gurevic, Ilya^; Islam, Zahidul^; Świderek, Katarzyna*; Trepka, Kai; Ghosh, Ananda; Moliner, Vicent; Kohen, Amnon. “Experimental and computational studies delineate the role for asparagine 177 in hydride transfer for E. coli thymidylate synthase.” (^authors contributed equally) ACS Catalysis. 2018, 8 (11), 10241-10253.

Islam, Zahidul; Strutzenberg, Timothy; Gurevic, Ilya; Kohen, Amnon. “Concerted versus step-wise mechanism in thymidylate synthase.” Journal of the American Chemical Society. 2014, 136, 9850-9853


Jacob Litman (Fellowship 2014-2016)

Kondratick, C. M., J. M. Litman, K. V. Shaffer, M. T. Washington and L. M. Dieckman (2018). Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring. Plos One 13(3), 15 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193333

*LuCore, Stephen D., Jacob M. Litman, Kyle T. Powers, S. Gao, Ava M. Lynn, William T. A. Tollefson, Timothy D. Fenn, M. T. Washington and Michael J. Schnieders (2015). Dead-End Elimination with a Polarizable Force Field Repacks PCNA Structures. Biophysical Journal 109(4), 816-826 https://www.sciencedirect.com/science/article/pii/S0006349515006761

*Nessler, I. J., J. M. Litman and M. J. Schnieders (2016). Toward polarizable AMOEBA thermodynamics at fixed charge efficiency using a dual force field approach: application to organic crystals. Physical Chemistry Chemical Physics https://pubs.rsc.org/en/content/articlelanding/2016/cp/c6cp02595a#!divAbstract


Joseph O'Brien (Fellowship 2017-2019)

Bodle, C. R., Hayes, M. P., O'Brien, J. B., and Roman, D. L. (2017) Development of a bimolecular luminescence complementation assay for RGS: G protein interactions in cells. Anal Biochem 522, 10-17

*Bodle, C. R., Schamp, J. H., O'Brien, J. B., Hayes, M. P., Wu, M., Doorn, J. A., and Roman, D. L. (2018) Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures. SLAS Discov 23, 363-374

*Sieng, M., Hayes, M. P., O'Brien, J. B., Andrew Fowler, C., Houtman, J. C., Roman, D. L., and Lyon, A. M. (2019) High-resolution structure of RGS17 suggests a role for Ca(2+) in promoting the GTPase-activating protein activity by RZ subfamily members. J Biol Chem 294, 8148-8160


Kyle Powers (Fellowship 2013-2015)

*Powers KT, Gildenberg MS, Washington MT. (2019) Modeling Conformationally Flexible Proteins With X-ray Scattering and Molecular Simulations. Comput Struct Biotechnol J. 17:570-578 https://www.ncbi.nlm.nih.gov/pubmed/31073392

*Powers KT, Lavering ED, Washington MT.  (2018) Conformational Flexibility of Ubiquitin-Modified and SUMO-Modified PCNA Shown by Full-Ensemble Hybrid Methods. J Mol Biol. 430(24):5294-5303 https://www.ncbi.nlm.nih.gov/pubmed/30381149

*Powers KT, Washington MT. (2018) Eukaryotic translesion synthesis: Choosing the right tool for the job. DNA Repair (Amst). 71:127-134 https://www.ncbi.nlm.nih.gov/pubmed/29385534

*Powers KT, Elcock AH, Washington MT. (2018) The C-terminal region of translesion synthesis DNA polymerase η is partially unstructured and has high conformational flexibility. Nucleic Acids Res. 46(4):2107-2120 https://www.ncbi.nlm.nih.gov/pubmed/29385534

*Powers KT, Washington MT. (2017) Analyzing the Catalytic Activities and Interactions of Eukaryotic Translesion Synthesis Polymerases. Methods Enzymol. 592:329-356 https://www.ncbi.nlm.nih.gov/pubmed/28668126

*Kondratick CM, Boehm EM, Dieckman LM, Powers KT, Sanchez JC, Mueting SR, Washington MT. (2016) Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis. PLoS One. 11(6):e0157023 https://www.ncbi.nlm.nih.gov/pubmed/27258147

*Boehm EM, Powers KT, Kondratick CM, Spies M, Houtman JC, Washington MT.  (2016)  The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1. J Biol Chem. 291(16):8735-44https://www.ncbi.nlm.nih.gov/pubmed/26903512


Juliana Quarterman (Fellowship 2017-2019)

*Juliana C. Quarterman, B. E. Givens, S. M. Geary, A. K. Salem. “Drug Eluting Degradable Coatings on Biomedical Implants.” Emerging Technologies for Biofabrication and Biomanufacturing. Ed. Utkan Demirci, Pu Chen, Rami El Assal. World Scientific Publishing Company, 2018. Book Chapter Submitted.

*R. Smith, W. Duan, J. Quarterman, A. Morris, C. Collie, M. Black, F. Toor, A. K. Salem. (2018) “Surface Modifying Doped Silicon Nanowire based Solar Cells for Applications in Biosensing.” Adv Mater Tech 1800349: 1-7.


Danielle Webb (Fellowship 2017-2019)

*Klarich Wong, K.L., Webb, D.T., Nagorzanski, M.R., Kolpin, D.R., Hladik, M.L., Cwiertny, D.M., LeFevre, G.H. (2019) Chlorinated byproducts of neonicotinoids and their metabolites: An unrecognized human exposure potential? Environ. Sci. Technol. Lett. 6(2): 98-105. https://doi.org/10.1021/acs.estlett.8b00706

*Denotes Publication supported by Fellowship