YEAR OF GRAD STUDY: 5th
MENTOR: Jonathon Doorn
SOURCES OF SUPPORT: Seachore and Ballard Dissertation Fellowship
Concordia University B.S. 2010 Chemistry
University of Iowa PhD 2015 Medicinal Chemistry
RESEARCH EXPERIENCE (prior to entering program):
Chemical research in synthesis of coordinated complexes for anticancer agents. Extensive research experience with cell biology, and stem cell science.
CURRENT RESEARCH ACTIVITIES (brief description):
As a member of a neurotoxicology lab, my project has been to focus on novel targets of an endogenous.
COURSES TAKEN (this graduate program):
fundamentals of gene expression, spectroscopy, mechanisms of organic reactions, pharmaceutical toxicology, drug discovery, enzyme reactions, analytical biochemistry.
POSTDOCTORAL TRAINING APPLIED FOR: N/A
APPLICATION(S) FOR POSTDOCTORAL FUNDING: N/A
Virginia F. Florang, Brigitte C Vanle, Josephine Schamp, Jonathan Doorn. Aldehyde Dehydrogenase Inhibition Generates a Reactive Dopamine Metabolite Autotoxic to Dopamine Neurons Parkinsonism & Related Disorders (review). Parkinsonism & Related Disorders. September 2013.
Brigitte C. Vanle and Jonathan Doorn. Enzyme Structure and Inactivation of
Glyceraldehyde-3-phosphate Dehydrogenase by 3,4- Dihydroxyphenylacetaldehyde. Chemical Research & Toxicology. (submitted)
Brigitte C. Vanle and Jonathan Doorn. Environmental Factors contributing to Parkinson’s Disease (in progress)
Eric A. Rodriguez, Brigitte C. Vanle, Michael Duffel, Jonathan Doorn. The effect of polychlorinated PCBs on neuronal cell lines. (in progress)