DEPT: Biochemistry
YEAR OF GRAD STUDY: 2001-2010
MENTOR: S. Ramaswamy
SOURCES OF SUPPORT: Medical Scientist Training Program Center for Biocatalysis and Bioprocessing
EDUCATION:
St. Olaf College MA 1997-2001 Mathematics & Chemistry
University of Iowa MD/PhD 2001-2010 Biochemistry PhD
Broadlawns Hospital 2010 Family Practice Internship
University of Missouri-Kansas City 2011-2014 Ophthalmology Residency
University of Pittsburgh 2014-2015 Glaucoma Fellowship
HONORS:
Phi Beta Kappa
TEACHING EXPERIENCE:
Teaching assistant during graduate school, lectures during residency & fellowship
RESEARCH EXPERIENCE (prior to entering program):
Research projects on computer graphics during high school. Research on ophthalmology image processing and CT/MRI analysis algorithms during college.
CURRENT RESEARCH ACTIVITIES (brief description):
I’m currently involved in numerous clinical ophthalmology projects including longitudinal analysis of glaucoma imaging tests, personalization of IOL constants for optimizing outcomes from cataract surgery, and image processing for evaluating glaucoma surgical techniques in model systems.
COURSES TAKEN (this graduate program):
all medical school courses; Biophysical Chemistry I & II, Principles of Molecular and Cellular Biology, Responsible Conduct in Research, Topics in Biochemistry, Introduction to Molecular Modeling, Perspectives on Biocatalysis
POSTDOCTORAL TRAINING APPLIED FOR:
University of Iowa Biochemistry / Dr. Plapp Enzymatics
University of Iowa Ophthalmology / Dr. Hageman AMD Genetics
APPLICATION(S) FOR POSTDOCTORAL FUNDING:
none
PUBLICATIONS: PLEASE LIST BELOW AND CONTINUE ON THE BACK OF THIS FORM:
E. N. Brown and N. A. Loewen. Treatment pathways and expert systems expected to improve patient care system-wide (2014). Ocular Surgery News, May 10, 9.
E. N. Brown and R. Krishna. Maximizing Care of the Underserved Glaucoma Patient Population (2014). Glaucoma Today, 38{9.
Rebenitsch, R. L., Brown, E. N., Binder, N. R., Jani, A., Bonhman, A. J., Krishna, R., Pikey, K.E_ect of topical loteprednol on intraocular pressure after Selective Laser Trabeculoplasty (2013). Ophthalmology and Therapy 2, 113{20.
Skeie, J. M., Brown, E.N., Martinez, H. D., Russell, S. R., Birkholz, E. S., Folk, J. C., Boldt, H. C., Gehrs, K. M., Stone, E. M., Wright, M. E., Mahajan, V. B. Proteomic analysis of vitreous biopsy techniques (2012). Retina, 2141{9.
Gehrs, K. M., J. R. Jackson, E. N. Brown, R. Allikmets, G. S. Hageman. Complement, age-related macular degeneration and a vision of the future (2010). Archives of Ophthalmology 128, 349{58.
Friemann, R., K. Lee, E. N. Brown, D. T. Gibson, H. Eklund, S. Ramaswamy. Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system (2009). Acta Crystallgr D Biol Crystallogr 65, 24{33.
Lord, R. L., L. Davis, E. L. Millam, E. N. Brown, C. O_erman, P. Wray, S. M. E. Green. Ab Initio Determinations of Photoelectron Spectra Including Vibronic Features. An Upper-Level Undergraduate Physical Chemistry Laboratory (2008). J Chem Educ 85, 1672{4.
Brown, E. N., R. Friemann, A. Karlsson, J. V. Parales, M. M. J. Couture, L. D. Eltis, and S. Ramaswamy. Determining Rieske cluster reduction potentials (2008). J Biol Inorg Chem 13, 1301.
Brown, E. N. Removing bias from solvent atoms in electron density maps (2008). J Applied Crystallography 41, 761{7.
Brown, E. N. and Ramaswamy, S. Quality of protein crystal structures (2007). Acta Crystallogr D Biol Crystallogr 63, 941{50.
Ferraro D. J., E. N. Brown, C. L. Yu, R. E. Parales, D. T. Gibson, and S. Ramaswamy (2007). Structural investigations of the ferredoxin and terminal oxygenase component of the biphenyl 2,3-dioxygenase from Sphingobium yanoikuyae B1. BMC Struct Biol 7, 10.
Yu C. L., W. Liu, D. J. Ferraro, E. N. Brown, J. V. Parales, S. Ramaswamy, G. J. Zylstra, D. T. Gibson, and R. E. Parales (2007). Puri_cation, characterization, and crystallization of the components of a biphenyl dioxygenase system from Sphingobium yanoikuyae B1. J Ind Microbiol Biotechnol 34, 311{24.
Brown, E. N., J. J. Camp, S. V. Patel, J. W. McLaren, W. M. Bourne, and R. A. Robb (2000). Automated stromal nerve rejection in corneal confocal images in vivo. Proc SPIE 3979, 1195{1200.