CBB offers an experienced professional staff and state-of-the-art fermentation and purification facilities to perform confidential contract services. Operations are smoothly transferred from the main facility to GMP. In 2004, CBB acquired the current Good Manufacturing Practices (cGMP) facility with three protein purification suites. In 2007, CBB completed a cGMP fermentation suite containing 30, 100 and 300-liter fermentors. The GMP facilities are located on the University of Iowa Research Park adjacent to the CBB's Research and Process Development Laboratory.

CBB is committed to working collaboratively with clients to deliver their products. CBB interacts with more than 60 different clients each year. On a weekly basis CBB schedules 6-10 project activities concurrently. CBB has long term collaborations and commitments with several clients, some of them spanning over 15 years and 40 separate projects. CBB clients cover the entire range of corporate size, and include the nation's foremost universities and institutions. Geographically, CBB-clients range from Europe to New Zealand; but majority are from the United States of America.

An experienced expert staff operates CBB’s state-of-the-art upstream and downstream processing facilities. The CBB develops, evaluates, optimizes, and scales up bio-based products in volumes ranging from 1 to 1,000-L. Typically, they bring research findings from the bench through the first stages of scale-up. The more than 20-member lab staff's extensive experience includes a wide-range of organisms, notably high-cell-density recombinant E.coli and Pichia pastoris. Products produced cover the complete range of interest - vaccines, enzymes, immobilized catalysts, antibiotics, therapeutics, nucleotides, polysaccharides, peptides, polymers, and biochemicals. The development process is rapid, economical and can be easily transferred to CBB cGMP Laboratory.

CBB produces bulk biopharmaceuticals for evaluation. The Center has considerable experience purifying fermentation-produced biological materials. Typical operations may include diafiltration, ultrafiltration, complex chromatographic separations, and lyophilization.

Clients find the CBB's business practices fast, efficient and easy. The period from initial contact to the start of work in the laboratory often takes only a few weeks. Typical projects start with a Confidentiality Agreement, allowing the exchange of necessary information. CBB follows this with a Service Agreement and/or proposal outlining the protocol, estimated costs and timing.