25th Annual CBB Conference
"Microbial Factories and Biocatalytic Science"
October 17-18, 2016
University of Iowa
Iowa Memorial Union, Iowa City, IA
Monday, October 17, 2016
Iowa Theater (1st Floor)
12:00 – 1:30 pm Registration – Hubbard Lobby (outside Iowa Theater, 1st floor IMU)
1:30 – 1:45 Opening Remarks:
Mark Arnold, Ph.D.,
Director, Center for Biocatalysis and Bioprocessing, Office of the Vice President for Research & Economic Development, University of Iowa Research Park, Coralville, IA
Professor and Edwin B. Green Chair in Laser Chemistry, Department of Chemistry, College of Liberal Arts & Sciences, University of Iowa, Iowa City, IA
1:45 – 2:30
David F. Wiemer, Ph.D., F. Wendell Miller Professor of Chemistry & Professor of Pharmacology, Department of Chemistry, College of Liberal Arts & Sciences, University of Iowa, Iowa City, IA
“Biologically active compounds based on the intermediates of isoprenoid biosynthesis
2:30 – 3:15
Robert Kerns, Ph.D., John L. & Carol E. Lach Chair in Drug Delivery Technology, Professor and Department Chair, Department of Pharmaceutical Sciences & Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA
“New Bioactive Glycoconjugates Derived From Chemical Modification of Sulfated Saccharides”
3:15 – 3:30 Break
3:30 – 4:15
Robert J. Linhardt, Ph.D.,
Ann and John H. Broadbent, Jr. ’59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering , Professor of Chemistry and Chemical Biology, Biology, Chemical and Biological Engineering and Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY
“Chemoenzymatic Synthesis of Heparin and Low Molecular Weight Heparins”
4:15 – 5:00
John W. Frost, Ph.D.,
Professor, Department of Chemistry, Michigan State University, East Lansing, MI
“Straight or Bent? Synthesis of Biobased Aromatics”
Ballroom (2nd Floor)
5:00 – 6:30 pm Social Gathering and Poster set up – Ballroom, 2nd Floor IMU
5:00 – 6:00 Fermentation facility tour– please register for tour online
6:00 – 7:30 Welcome Dinner/Buffet – Ballroom, 2nd Floor IMU
7:30 – 8:15 CBB Past, Present and Future: Comments from CBB Directors
Jack Rosazza, Ph.D., Mani Subramanian, Ph.D., Mark Arnold Ph.D.
Tuesday, October 18, 2016
Iowa Theater (1st Floor)
7:30 – 8:00 am Registration – Hubbard Lobby (outside Iowa Theater, 1st floor IMU)
7:30 – 8:30 Continental Breakfast – across from Iowa Theater, 1st floor IMU
8:30 Program – Iowa Theater, 1st floor IMU
Introduction and Welcome
Mark Arnold, Ph.D.,
Director, Center for Biocatalysis and Bioprocessing, Office of the Vice President for Research & Economic Development, University of Iowa Research Park, Coralville, IA
Professor and Edwin B. Green Chair in Laser Chemistry, Department of Chemistry, College of Liberal Arts & Sciences, University of Iowa, Iowa City, IA
8:45– 9:30
Maria Spies, Ph.D.,
Associate Professor, Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA
“Single-molecule studies of FeS DNA helicases: kinetics, conformational dynamics and molecular mechanisms”
9:30– 10:15
Eric Nuxoll, Ph.D.,
Associate Professor, Department of Chemical and Biological Engineering, College of Engineering, University of Iowa, Iowa City, IA
“Wireless Deactivation of Bacterial Biofilms”
10:15– 10:30 Break – Iowa Theater Lobby, 1st floor IMU
10:30– 11:15
Ronen Tchelet Ph.D.,
VP Research & Business Development, Dyadic International Inc. Jupiter, FL
“C1 – the journey of more productive cell expression”
11:15– 12:00
Laura R. Jarboe, Ph.D.,
Associate Professor, Department of Chemical and Biological Engineering Chair, Interdepartmental Microbiology Graduate Program, Iowa State University, Ames, IA
“Metabolic Engineering of Robust Microbial Cell Factories”
12:00– 1:30 Lunch – Ballroom, 2nd Floor IMU
External Advisory Board-Penn State Room
Afternoon Session – Iowa Theater, 1st Floor IMU
1:30 – 2:45 CBB/NIH Fellow Presentations
Benjamin J. Foust, Professor David F. Weimer Research Group, Department of Chemistry, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA
“A New Motif for Inhibitors of Geranylgeranyl Diphosphate Synthase”
Mark S. Miller, Professor Adrian H. Elcock Research Group, Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA
“Re-parameterization of Protein Force Fields Guided by Osmotic Coefficient Measurements from Molecular Dynamics Simulations”
Nicholas Vance, Professor M. Ashley Spies Research Group, Department of Pharmaceutical Sciences & Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA
“Probing allosteric regulation of an executioner caspase”
Erica N.B. Ricker, Professor Eric Nuxoll Research Group, Department of Chemical and Biochemical Engineering, College of Engineering, University of Iowa, Iowa City, IA
"The Synergistic Effects of Antibiotics and Heat on Pseudomonas aeruginosa Biofilms"
2:45 – 3:00 Concluding remarks
3:00 – 5:00 Poster Session – Wine/hors d'oeuvres, Ballroom 2nd Floor IMU
Announcement of Usha Balakrishnan Award Winner
Announcement of Director’s Award Winner
Announcement of Mani Subramanian Award Winner
5:00 Adjourn