Bioprocessing Services
Fermentation, protein purification, & cGMP production for Phase-1 clinical trials
Academic Opportunities
Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available
Annual Conference
The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.
30 +
Years of Manufacturing Experience
265 +
Fellowships Awarded to Students
55 +
Associated UI Faculty
Microbial Manufacturing Services
As a microbial manufacturing & bioprocessing facility, our diverse team at the CBB specializes in cGMP and non-cGMP production of protein products for various business, commercial, and research purposes. We have years of experience in developing bioprocesses for scaling up fermentation & protein purification (including difficult to purified inclusion bodies), cGMP manufacturing, cell banking, instrumentation, and more.
All critical equipment within the facility passed Factory Acceptance Tests (FAT), Installation Qualification (IQ), and Operational Qualification (OQ). This facility is open for audit by clients.
With many successful campaigns over the years, the CBB has become a trusted partner for our local & international clients alike.
Non-cGMP Facility
Our non-cGMP Facility is fully equipped with advanced technologies & instruments to provide both upstream & downstream process development services to our clients, from strain development to large scale manufacturing. All projects are carried out by full-time staff with years of experience in research & process development.
cGMP Facility
The cGMP Manufacturing Facility at CBB is capable of producing protein products for Phase-1 clinical trials. This cGMP Manufacturing Facility and the Non-cGMP Facility share similar equipment, allowing for efficient process transfer between the two facilities. Our facility strictly follows the 2008 FDA guidance for cGMP manufacturing of materials for Phase-1 investigational drugs.
"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."
Educational & Training Opportunities
Every year, the CBB awards multiple fellowships to predoctoral student applicants to support their graduate research in the biocatalytic sciences (see definition). In addition to our own CBB fellowship program, the CBB also administers NIH fellowships.
Both NIH and CBB fellowships are designed to promote training focusing on the applications of biological & physical sciences to conduct interdisciplinary research in all domains of biotechnology.
Supportive Faculty Trainers
Our fellows are students working in a CBB-associated faculty's laboratory at The University of Iowa. Faculty help students obtain internships, build their work portfolios, and prepare job application materials.
Predoctoral graduate students are encouraged to discuss with their major advisors as soon as possible regarding the application process. Students in their 1st and 2nd year are given priority.
"Center of Biocatalysis and Bioprocessing was very generous to award to me a 2-year Pre-Doctoral Fellowship in biotechnology for my PhD at UIOWA. Furthermore, I had a great opportunity of visit CBB facility and learn about protein purification services for Phase 1 clinical trial and downstream purification and bioprocessing."