Welcome to CBB

The Center for Biocatalysis and Bioprocessing (CBB) is a microbial biomanufacturing and research facility that bridges the gap between laboratory discovery and commercial-scale bioprocessing solutions. Located at the University of Iowa, CBB offers microbial fermentation, recombinant protein expression, and downstream protein purification services for a wide variety of clients, including international corporations and early-stage start-up companies. For clients interested in clinical applications, a cGMP suite is available to manufacture of proteins under the quality standards defined by the U.S. Food and Drug Administration specifically for Phase 1 clinical trials.  

 

By combining the technical capabilities of a university-based pilot-scale CDMO with the expertise of affiliated faculty and researchers, the CBB serves as a trusted partner to biotech startups, vendors for the life science community, pharmaceutical companies, and academic innovators. Our facility supports innovation across multiple sectors, supporting the development and scale-up of protein-based therapeutics, specialty enzymes, reagent proteins, and other next-generation biologics. In addition, CBB plays a key role in bioprocessing workforce development through graduate training and NIH-funded biomanufacturing fellowships, thereby helping to shape the future of the biotech and life sciences industries.  

We Work with a Wide Range of Clients across the Biotech, Life Sciences, and Pharmaceutical Spaces

We welcome clients from diverse industry sectors, including biotech startups seeking scalable biomanufacturing, academic research laboratories advancing translational science, life science vendors supporting basic and applied research worldwide, as well as large multinational pharmaceutical manufacturers and government agencies involved in drug development and public health initiatives. Our services are accessible to clients regardless of geographic location, ensuring professional support for protein production, purification, and bioprocess development. 

How to Start a Service with CBB?

We’re here to support your project every step of the way. Getting started with the Center for Biocatalysis and Bioprocessing (CBB) is simple. Clients can request services by completing our Client Request Form online. After submitting the form, a CBB representative will contact you within 2-3 business days to confirm your request and to schedule an initial consultation.  

 

During this initial consultation, your project requirements will be discussed in a non-confidential manner. CBB will then evaluate whether our facility can meet your specific needs. If so, a Confidential Disclosure Agreement (CDA) template will be provided for your consideration. In parallel, we will share a ballpark estimate of the costs for your project.  
 
Upon execution of the CDA, a more in-depth discussion will be used to provide a more accurate assessment of the costs for CBB’s bioprocessing services. Services can begin once a Master Service Agreement is in place and a Project Ordered is created specifically tailored toward your bioprocessing needs.  
 
Our team will be with you through every step to ensure a smooth and compliant bioprocessing experience.  

Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience
CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students
CBB Operator Working in the Lab

55 +

Associated UI Faculty

News

Maria Spies, Ph.D.

Saturday, November 15, 2025

Tyler J. Woodward

Wednesday, October 15, 2025

Hossein Zare

Wednesday, October 15, 2025

Reza Nejadnik

Wednesday, October 15, 2025

Meet Some of Our Associated Faculty

Office of VP for Research Events

Data Visualization in Stata with Chase LaSpisa promotional image

Data Visualization in Stata with Chase LaSpisa

Tuesday, March 31, 2026 2:00pm to 3:30pm
Virtual
This virtual workshop will introduce how to visualize data in multiple ways using Stata. Various data visualization examples will be demonstrated during the workshop. By the end of this workshop, participants will be able to create and edit presentation or publication quality visualizations (e.g., bar graphs, box plots, scatterplots) using Stata code. This is an introductory workshop appropriate for those with only basic familiarity with Stata. Example code will be provided.
Pivot Administrative Features: Connect Your Researchers to Funding Opportunities promotional image

Pivot Administrative Features: Connect Your Researchers to Funding Opportunities

Tuesday, March 31, 2026 2:00pm to 3:00pm
Virtual

Are you looking for ways to assist researchers with identifying grant funding opportunities? Are you wanting to learn more about the enhanced administrative features of Pivot? Join us for this virtual information session on Tuesday, March 31 from 2 to 3 p.m.

Topics include crafting and saving funding opportunity searches, creating calendars and newsletters, sharing and tracking opportunities, editing profiles, and enabling weekly email alerts. We will also discuss how to request access to the...

College of Medicine Events

Frontiers in Obesity, Diabetes and Metabolism Seminar - Vitor Lira, PhD  promotional image

Frontiers in Obesity, Diabetes and Metabolism Seminar - Vitor Lira, PhD

Monday, March 30, 2026 1:00pm to 2:00pm
Carver Biomedical Research Building

Vitor Lira, PhD, Associate Professor in the Department of Health, Sport and Human Physiology will be giving a talk titled, "Emerging Roles of ULK1/2 in The Dynamic Control of Protein Metabolism in Skeletal Muscle."

Molecular Physiology and Biophysics Seminar, Tatjana Jakobs, MD promotional image

Molecular Physiology and Biophysics Seminar, Tatjana Jakobs, MD

Tuesday, March 31, 2026 9:30am to 10:30am
Bowen Science Building

College of Pharmacy Events

Iowa Reception at APhA Annual Meeting & Exposition

Sunday, March 29, 2026 5:30pm to 7:00pm
JW Marriott

Join your Iowa pharmacy family, friends, and colleagues from across the country at the Iowa Reception during the 2026 APhA Annual Meeting and Exhibition. This event will recognize Iowa award recipients and leadership, including outgoing APhA President Randy McDonough.

Hosted by IPA, Drake University College of Pharmacy and Health Sciences, and UI College of Pharmacy.

College of Pharmacy PSET Seminar Series: Yuan Zhang, PhD promotional image

College of Pharmacy PSET Seminar Series: Yuan Zhang, PhD

Tuesday, March 31, 2026 11:30am
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics (PSET) in the College of Pharmacy will host a seminar presented by: 

Yuan Zhang, PhD
Assistant Professor
Department of Chemistry
Iowa State University
Ames, Iowa

All are welcome to attend. No pre-registration required.