Welcome to CBB

The Center for Biocatalysis and Bioprocessing (CBB) is a microbial biomanufacturing and research facility that bridges the gap between laboratory discovery and commercial-scale bioprocessing solutions. Located at the University of Iowa, CBB offers microbial fermentation, recombinant protein expression, and downstream protein purification services for a wide variety of clients, including international corporations and early-stage start-up companies. For clients interested in clinical applications, a cGMP suite is available to manufacture of proteins under the quality standards defined by the U.S. Food and Drug Administration specifically for Phase 1 clinical trials.  

 

By combining the technical capabilities of a university-based pilot-scale CDMO with the expertise of affiliated faculty and researchers, the CBB serves as a trusted partner to biotech startups, vendors for the life science community, pharmaceutical companies, and academic innovators. Our facility supports innovation across multiple sectors, supporting the development and scale-up of protein-based therapeutics, specialty enzymes, reagent proteins, and other next-generation biologics. In addition, CBB plays a key role in bioprocessing workforce development through graduate training and NIH-funded biomanufacturing fellowships, thereby helping to shape the future of the biotech and life sciences industries.  

We Work with a Wide Range of Clients across the Biotech, Life Sciences, and Pharmaceutical Spaces

We welcome clients from diverse industry sectors, including biotech startups seeking scalable biomanufacturing, academic research laboratories advancing translational science, life science vendors supporting basic and applied research worldwide, as well as large multinational pharmaceutical manufacturers and government agencies involved in drug development and public health initiatives. Our services are accessible to clients regardless of geographic location, ensuring professional support for protein production, purification, and bioprocess development. 

How to Start a Service with CBB?

We’re here to support your project every step of the way. Getting started with the Center for Biocatalysis and Bioprocessing (CBB) is simple. Clients can request services by completing our Client Request Form online. After submitting the form, a CBB representative will contact you within 2-3 business days to confirm your request and to schedule an initial consultation.  

 

During this initial consultation, your project requirements will be discussed in a non-confidential manner. CBB will then evaluate whether our facility can meet your specific needs. If so, a Confidential Disclosure Agreement (CDA) template will be provided for your consideration. In parallel, we will share a ballpark estimate of the costs for your project.  
 
Upon execution of the CDA, a more in-depth discussion will be used to provide a more accurate assessment of the costs for CBB’s bioprocessing services. Services can begin once a Master Service Agreement is in place and a Project Ordered is created specifically tailored toward your bioprocessing needs.  
 
Our team will be with you through every step to ensure a smooth and compliant bioprocessing experience.  

Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience
CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students
CBB Operator Working in the Lab

55 +

Associated UI Faculty

News

Maria Spies, Ph.D.

Saturday, November 15, 2025

Tyler J. Woodward

Wednesday, October 15, 2025

Hossein Zare

Wednesday, October 15, 2025

Reza Nejadnik

Wednesday, October 15, 2025

Meet Some of Our Associated Faculty

Office of VP for Research Events

Association of Ancient Historians Meeting 2026 promotional image

Association of Ancient Historians Meeting 2026

Thursday, April 16 to Saturday, April 18, 2026 (all day)
University of Iowa
Association of Ancient Historians Meeting 2026 supported by the Department of History, the College of Arts and Sciences, the Obermann Center, and the Perry A. and Helen J. Bond Fund for Interdisciplinary Interaction at the University of Iowa

Spring 2026 IRB Office Hours

Thursday, April 16, 2026 10:00am to 12:00pm
Virtual
IRB Office Hours are for all UI faculty, staff, and Investigators, HawkIRB delegates, and research team members involved with Human Subjects research.

College of Medicine Events

REDCap Data Handling

Thursday, April 16, 2026 10:00am to 11:00am
Virtual

This is the sixth and final step in the REDCap training series. In this training we won't use REDCap at all. Instead, we will cover ways to view and manage your exported REDCap data in Microsoft Excel and Sublime Text such as:

Populating data from one Excel sheet to another with vlookup()

Seeing specific data with column sorting and filtering

Ensuring data is cohesive by creating tables

Looking at how data relates to other data by creating pivot tables

Transforming unusable data to a usable format...

Fountain Lobby Blood Drive  promotional image

Fountain Lobby Blood Drive

Thursday, April 16, 2026 11:00am to 4:00pm
General Hospital
The DeGowin Blood Center is hosting a blood drive from 11 a.m. to 4 p.m. on April 16th, 2026, at the Fountain Lobby in the ground floor of the main hospital.

College of Pharmacy Events

Neuroscience and Pharmacology Workshop - Nathan Gentilman (Roman Lab) and Hannah Hazzard (Gumusoglu Lab) promotional image

Neuroscience and Pharmacology Workshop - Nathan Gentilman (Roman Lab) and Hannah Hazzard (Gumusoglu Lab)

Thursday, April 16, 2026 12:30pm to 1:30pm
Medical Education Research Facility

Per- and Polyfluoroalkyl Substances Alter GPCR Activity

Nathan Gentilmann
Pharmaceutical Sciences & Experimental Therapeutics PhD Student
Dr. Dave Roman Lab

Extracellular vesicle interactions with fetal brain microglia

Hannah Hazzard
Neuroscience PhD Student
Dr. Serena Banu Gumusoglu's Lab

2026 MIKIW Medicinal Chemistry Conference at the UI College of Pharmacy promotional image

2026 MIKIW Medicinal Chemistry Conference at the UI College of Pharmacy

Friday, April 17 to Sunday, April 19, 2026 (all day)
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics at the University of Iowa, will host the 63rd Annual Medicinal Chemistry Meeting-in-miniature.

MIKIW is the longest-running and largest regional medicinal chemistry conference in the United States. The meeting integrates over 200 graduate students, post-doctoral fellows, and faculty members from the Universities of Minnesota, Illinois at Chicago, Kansas, Iowa and Wisconsin. The two-day, multidisciplinary conference exposes...