Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience

CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students

CBB Operator Working in the Lab

55 +

Associated UI Faculty

Microbial Manufacturing Services

As a microbial manufacturing & bioprocessing facility, our diverse team at the CBB specializes in cGMP and non-cGMP production of protein products for various business, commercial, and research purposes. We have years of experience in developing bioprocesses for scaling up fermentation & protein purification (including difficult to purified inclusion bodies), cGMP manufacturing, cell banking, instrumentation, and more. 

All critical equipment within the facility passed Factory Acceptance Tests (FAT), Installation Qualification (IQ), and Operational Qualification (OQ). This facility is open for audit by clients. 

With many successful campaigns over the years, the CBB has become a trusted partner for our local & international clients alike.

Request Services Now!

We have worked with clients ranging from large pharmaceutical companies to biotech startups of all sizes to virtual companies, academic research labs, and governmental agencies. Our facility produces protein-based products for all sorts of purposes, including Phase-1 clinical trials. The quality of all manufactured products are ensured by our dedicated QA/QC team. 

CBB Operator Working in the Lab

Non-cGMP Facility

Our non-cGMP Facility is fully equipped with advanced technologies & instruments to provide both upstream & downstream process development services to our clients, from strain development to large scale manufacturing. All projects are carried out by full-time staff with years of experience in research & process development. 

CBB Operator Working in the Lab

cGMP Facility

The cGMP Manufacturing Facility at CBB is capable of producing protein products for Phase-1 clinical trials. This cGMP Manufacturing Facility and the Non-cGMP Facility share similar equipment, allowing for efficient process transfer between the two facilities. Our facility strictly follows the 2008 FDA guidance for cGMP manufacturing of materials for Phase-1 investigational drugs. 

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

Educational & Training Opportunities

Every year, the CBB awards multiple fellowships to predoctoral student applicants to support their graduate research in the biocatalytic sciences (see definition). In addition to our own CBB fellowship program, the CBB also administers NIH fellowships. 

Both NIH and CBB fellowships are designed to promote training focusing on the applications of biological & physical sciences to conduct interdisciplinary research in all domains of biotechnology. 

Learn More About Our Fellowships

Most of our fellows have successfully entered the biotech job market right after graduation because they not only graduated with multiple journal publications, but also with industrial internship experience. 

Supportive Faculty Trainers

Our fellows are students working in a CBB-associated faculty's laboratory at The University of Iowa. Faculty help students obtain internships, build their work portfolios, and prepare job application materials. 

Predoctoral graduate students are encouraged to discuss with their major advisors as soon as possible regarding the application process. Students in their 1st and 2nd year are given priority.

Supporting Fellows Beyond Graduation

Once a CBB fellow, always a CBB fellow-From academic to personal to professional development, the CBB & our committed faculty provide continuous guidance & mentorship to our fellows even after their graduation.

 

"Center of Biocatalysis and Bioprocessing was very generous to award to me a 2-year Pre-Doctoral Fellowship in biotechnology for my PhD at UIOWA. Furthermore, I had a great opportunity of visit CBB facility and learn about protein purification services for Phase 1 clinical trial and downstream purification and bioprocessing."

Meet Some of Our Associated Faculty

Office of VP for Research Events

The K Award Ecosystem: Writing a Competitive K Award 2024-25 Seminar promotional image

The K Award Ecosystem: Writing a Competitive K Award 2024-25 Seminar

Friday, October 4, 2024 8:30am to 12:30pm
Virtual
A competitive NIH Career Development K Award fits together like a complex ecosystem. This seminar will walk you through all the parts of the proposal, emphasizing the purpose of each part and how different sections must mesh. Note: the general concepts also apply to many aspects of Fellowship (F31/F32) applications. K Award Ecosystem Seminar The Research Development Office and the Institute for Clinical and Translational Science are hosting a virtual NIH K Award grant writing seminar, The K...
Spotlight on faculty-student research collaborations at Iowa promotional image

Spotlight on faculty-student research collaborations at Iowa

Friday, October 4, 2024 1:30pm to 3:30pm
University Capitol Centre
Students and their faculty mentors will present their work in the global health realm and will discuss their working collaboration and research focus. Light refreshments will be served.

College of Medicine Events

Progress 2024: Learning Together in the 21st Century promotional image

Progress 2024: Learning Together in the 21st Century

Thursday, October 3 to Friday, October 4, 2024 (all day)
Hyatt Regency Place
Attend the PROGRESS 2024 Conference and get 11.5 ACPE credits! Emphasizing the interprofessional team approach to patient care, this program combines annual internal medicine and pharmacy continuing education programs. In person attendance only. DATES: Thursday, Oct. 3, 2024, 7:15 a.m. - 4:30 p.m.; Friday, Oct. 4, 2024, 7:15 a.m. - 3:15 p.m.  LOCATION & PARKING: Hyatt Regency Coralville 300 E. 9th Street Coralville, IA 52241 Parking is available in the garage adjacent to the hotel at...
Seminar Series Commemorating the Lasting Impact of the Wendell Johnson Speech and Hearing Center promotional image

Seminar Series Commemorating the Lasting Impact of the Wendell Johnson Speech and Hearing Center

Friday, October 4, 2024 12:00pm to 1:00pm
Wendell Johnson Speech and Hearing Center
Weekly Professional Seminar related to Hearing, Speech, and Language Sciences and Clinical Practice.

College of Pharmacy Events

Progress 2024: Learning Together in the 21st Century promotional image

Progress 2024: Learning Together in the 21st Century

Thursday, October 3 to Friday, October 4, 2024 (all day)
Hyatt Regency Place
Attend the PROGRESS 2024 Conference and get 11.5 ACPE credits! Emphasizing the interprofessional team approach to patient care, this program combines annual internal medicine and pharmacy continuing education programs. In person attendance only. DATES: Thursday, Oct. 3, 2024, 7:15 a.m. - 4:30 p.m.; Friday, Oct. 4, 2024, 7:15 a.m. - 3:15 p.m.  LOCATION & PARKING: Hyatt Regency Coralville 300 E. 9th Street Coralville, IA 52241 Parking is available in the garage adjacent to the hotel at...
College of Pharmacy PSET Seminar Series: Sarven Sabunciyan, PhD promotional image

College of Pharmacy PSET Seminar Series: Sarven Sabunciyan, PhD

Tuesday, October 8, 2024 11:30am
College of Pharmacy Building
The Department of Pharmaceutical Sciences and Experimental Therapeutics in the College of Pharmacy will host a seminar by: Sarven Sabunciyan, PhD Associate Professor Department of Pediatrics Johns Hopkins Baltimore, Maryland Seminar Title: "Developing Biomarkers for Psychiatric Disorders: Detecting Brain Pathology via Extracellular Vesicle mRNAs Circulating in Blood” All are welcome to attend.