Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

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Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

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Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

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CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience

CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students

CBB Operator Working in the Lab

55 +

Associated UI Faculty

Microbial Manufacturing Services

As a microbial manufacturing & bioprocessing facility, our diverse team at the CBB specializes in cGMP and non-cGMP production of protein products for various business, commercial, and research purposes. We have years of experience in developing bioprocesses for scaling up fermentation & protein purification (including difficult to purified inclusion bodies), cGMP manufacturing, cell banking, instrumentation, and more. 

All critical equipment within the facility passed Factory Acceptance Tests (FAT), Installation Qualification (IQ), and Operational Qualification (OQ). This facility is open for audit by clients. 

With many successful campaigns over the years, the CBB has become a trusted partner for our local & international clients alike.

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We have worked with clients ranging from large pharmaceutical companies to biotech startups of all sizes to virtual companies, academic research labs, and governmental agencies. Our facility produces protein-based products for all sorts of purposes, including Phase-1 clinical trials. The quality of all manufactured products are ensured by our dedicated QA/QC team. 

Client Request Form
CBB Operator Working in the Lab

Non-cGMP Facility

Our non-cGMP Facility is fully equipped with advanced technologies & instruments to provide both upstream & downstream process development services to our clients, from strain development to large scale manufacturing. All projects are carried out by full-time staff with years of experience in research & process development. 

CBB Operator Working in the Lab

cGMP Facility

The cGMP Manufacturing Facility at CBB is capable of producing protein products for Phase-1 clinical trials. This cGMP Manufacturing Facility and the Non-cGMP Facility share similar equipment, allowing for efficient process transfer between the two facilities. Our facility strictly follows the 2008 FDA guidance for cGMP manufacturing of materials for Phase-1 investigational drugs. 

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

Educational & Training Opportunities

Every year, the CBB awards multiple fellowships to predoctoral student applicants to support their graduate research in the biocatalytic sciences (see definition). In addition to our own CBB fellowship program, the CBB also administers NIH fellowships. 

Both NIH and CBB fellowships are designed to promote training focusing on the applications of biological & physical sciences to conduct interdisciplinary research in all domains of biotechnology. 

Learn More About Our Fellowships

Most of our fellows have successfully entered the biotech job market right after graduation because they not only graduated with multiple journal publications, but also with industrial internship experience. 

Fellowship Requirements

Supportive Faculty Trainers

Our fellows are students working in a CBB-associated faculty's laboratory at The University of Iowa. Faculty help students obtain internships, build their work portfolios, and prepare job application materials. 

Predoctoral graduate students are encouraged to discuss with their major advisors as soon as possible regarding the application process. Students in their 1st and 2nd year are given priority.

Supporting Fellows Beyond Graduation

Once a CBB fellow, always a CBB fellow-From academic to personal to professional development, the CBB & our committed faculty provide continuous guidance & mentorship to our fellows even after their graduation.


Participating Departments

"Center of Biocatalysis and Bioprocessing was very generous to award to me a 2-year Pre-Doctoral Fellowship in biotechnology for my PhD at UIOWA. Furthermore, I had a great opportunity of visit CBB facility and learn about protein purification services for Phase 1 clinical trial and downstream purification and bioprocessing."

Meet Some of Our Associated Faculty

Office of VP for Research Events

IRB Efficiency Initiative Information Session

Wednesday, May 22, 2024 12:00pm to 1:00pm
IRB Efficiency Initiative Information Session The Human Subjects Office invites the UI research community to attend monthly information sessions about the IRB Efficiency Initiative on the fourth Wednesday of the month, from noon to 1 p.m. We will discuss the changes and demonstrate HawkIRB enhancements being implemented to streamline the IRB review process. The monthly session will cover upcoming enhancements and their expected rollout dates. Please join us to learn more about the IRB Efficiency Initiative.

Spring 2024 Office Hours

Wednesday, May 22, 2024 2:00pm to 4:00pm
Office Hours: IRB Office Hours are for all UI faculty, staff, and Investigators, HawkIRB delegates, and research team members involved with Human Subjects research. No appointment necessary. First come, first served; computers are available. HSO Staff will be available to: 1. Answer questions about conducting human subjects research. 2. Provide guidance and answer questions about the electronic application forms in the HawkIRB system. 3. Provide suggestions and guidance about study procedures that are in compliance with federal regulations and the UI IRB policies. 4. Provide guidance and answer questions about the submission of industry-initiated and industry-sponsored research projects to Western IRB (WIRB).

College of Medicine Events

ACB Seminar Series - Matthew Kennedy, PhD promotional image

ACB Seminar Series - Matthew Kennedy, PhD

Wednesday, May 22, 2024 11:00am to 12:00pm
Medical Education Research Facility
Dr. Matthew Kennedy, a Professor of Pharmacology from the University of Colorado's School of Medicine, will present a seminar titled "New Approaches for Investigating and Manipulating the Molecular Organization of Neuronal Synapses."

Internal Medicine Grand Rounds

Thursday, May 23, 2024 12:00pm to 1:00pm
General Hospital
DiBona Award Lecture: "TBA" by Bill Nauseef, MD, Emeritus Professor of Internal Medicine-Infectious Diseases

College of Pharmacy Events

54th Annual Pharmaceutics Graduate Student Research Meeting (PGSRM) promotional image

54th Annual Pharmaceutics Graduate Student Research Meeting (PGSRM)

Thursday, June 6 to Friday, June 7, 2024 (all day)
College of Pharmacy Building
The Division of Pharmaceutical Sciences at the University of Iowa will be hosting the 54th Annual Pharmaceutics Graduate Student Research Meeting (PGSRM). We are delighted to bring experts from academia and industry together with students to focus on the ideas and approaches enveloping big data pharmaceutical studies.  Theme: "Pharmaceutics on the Horizon: Innovation, Application, and Collaboration" *Registration coming soon!*
The 20th Midwest Social and Adminstrative Pharmacy Conference promotional image

The 20th Midwest Social and Adminstrative Pharmacy Conference

Monday, June 17 to Wednesday, June 19, 2024 (all day)
College of Pharmacy Building
The Midwest Social and Administrative Pharmacy Conference has a rich history that traces back to its inaugural event in 1985. The first gathering, known as the Midwest Pharmacy Administration Conference, was organized and hosted by faculty at Purdue University. This initial meeting took place at a pivotal time when the history of pharmacy administration as a discipline was coalescing. The conference stemmed from a recognition that pharmacy schools and graduate programs in the Midwest played a...