Welcome to CBB

The Center for Biocatalysis and Bioprocessing (CBB) is a microbial biomanufacturing and research facility that bridges the gap between laboratory discovery and commercial-scale bioprocessing solutions. Located at the University of Iowa, CBB offers microbial fermentation, recombinant protein expression, and downstream protein purification services for a wide variety of clients, including international corporations and early-stage start-up companies. For clients interested in clinical applications, a cGMP suite is available to manufacture of proteins under the quality standards defined by the U.S. Food and Drug Administration specifically for Phase 1 clinical trials.  

 

By combining the technical capabilities of a university-based pilot-scale CDMO with the expertise of affiliated faculty and researchers, the CBB serves as a trusted partner to biotech startups, vendors for the life science community, pharmaceutical companies, and academic innovators. Our facility supports innovation across multiple sectors, supporting the development and scale-up of protein-based therapeutics, specialty enzymes, reagent proteins, and other next-generation biologics. In addition, CBB plays a key role in bioprocessing workforce development through graduate training and NIH-funded biomanufacturing fellowships, thereby helping to shape the future of the biotech and life sciences industries.  

We Work with a Wide Range of Clients across the Biotech, Life Sciences, and Pharmaceutical Spaces

We welcome clients from diverse industry sectors, including biotech startups seeking scalable biomanufacturing, academic research laboratories advancing translational science, life science vendors supporting basic and applied research worldwide, as well as large multinational pharmaceutical manufacturers and government agencies involved in drug development and public health initiatives. Our services are accessible to clients regardless of geographic location, ensuring professional support for protein production, purification, and bioprocess development. 

How to Start a Service with CBB?

We’re here to support your project every step of the way. Getting started with the Center for Biocatalysis and Bioprocessing (CBB) is simple. Clients can request services by completing our Client Request Form online. After submitting the form, a CBB representative will contact you within 2-3 business days to confirm your request and to schedule an initial consultation.  

 

During this initial consultation, your project requirements will be discussed in a non-confidential manner. CBB will then evaluate whether our facility can meet your specific needs. If so, a Confidential Disclosure Agreement (CDA) template will be provided for your consideration. In parallel, we will share a ballpark estimate of the costs for your project.  
 
Upon execution of the CDA, a more in-depth discussion will be used to provide a more accurate assessment of the costs for CBB’s bioprocessing services. Services can begin once a Master Service Agreement is in place and a Project Ordered is created specifically tailored toward your bioprocessing needs.  
 
Our team will be with you through every step to ensure a smooth and compliant bioprocessing experience.  

Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience
CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students
CBB Operator Working in the Lab

55 +

Associated UI Faculty

News

Maria Spies, Ph.D.

Saturday, November 15, 2025

Tyler J. Woodward

Wednesday, October 15, 2025

Hossein Zare

Wednesday, October 15, 2025

Reza Nejadnik

Wednesday, October 15, 2025

Meet Some of Our Associated Faculty

Office of VP for Research Events

Registration Deadline: Junior Faculty and Graduate Student Session with Walter Biggins, Obermann Editor-in-Residence promotional image

Registration Deadline: Junior Faculty and Graduate Student Session with Walter Biggins, Obermann Editor-in-Residence

Wednesday, September 30, 2026 (all day)
111 Church Street

University of Iowa junior faculty and graduate students at all stages are invited to join Walter Biggins—editor-in-chief at the University of Pennsylvania Press—for a light breakfast and a conversation about turning an article, thesis, or dissertation into a book on Tuesday, Oct. 6, from 9–10:30 a.m. at the Obermann Center for Advanced Studies library. Please bring any questions you have about that process or about scholarly publishing in general.

Register by Wednesday, September 30.

Biggins is...

RSVP Deadline: AMA with Walter Biggins, Obermann Editor-in-Residence promotional image

RSVP Deadline: AMA with Walter Biggins, Obermann Editor-in-Residence

Wednesday, September 30, 2026 (all day)
111 Church Street

UI faculty, students, and staff are invited to attend ask-me-anything group discussions with Walter Biggins—editor-in-chief at University of Pennsylvania Press—at 1 p.m. and 3 p.m. on Monday, Oct. 1 at the Obermann Center for Advanced Studies. Questions might address finding an editor, pitching a book, writing a book proposal, how the publishing process works, etc.

There will be two back-to-back discussions; you may attend one or both.

Please RSVP by Wednesday, September 30.

Free and open to all.

Bi...

College of Medicine Events

ACB Seminar Series - Dr. Bhagaban Mallik  promotional image

ACB Seminar Series - Dr. Bhagaban Mallik

Wednesday, September 30, 2026 9:30am to 10:30am
Bowen Science Building

Dr. Bhagaban Mallik, an Assistant Research Scientist in the Frank Lab, will present a seminar titled "Differential Roles of Intracellular Calcium and Metabolic Energy in Phasic MN-Is and Tonic MN-Ib Motor Neurons."

Biochemistry Seminar: "Illuminating the Biochemical Activity Architecture of the Cell" promotional image

Biochemistry Seminar: "Illuminating the Biochemical Activity Architecture of the Cell"

Thursday, October 1, 2026 10:30am to 11:20am
Medical Education Research Facility

"Illuminating the Biochemical Activity Architecture of the Cell"

Presented by

Jin Zhang, Ph.D.
Professor of Pharmacology
University of California San Diego

College of Pharmacy Events

Progress 2026: Learning Together in the 21st Century promotional image

Progress 2026: Learning Together in the 21st Century

Thursday, October 1 to Friday, October 2, 2026 (all day)
Hyatt Regency Place

Overview:
Emphasizing the interprofessional team approach to patient care, the annual Progress conference combines internal medicine and pharmacy continuing education programs into a single multi-track program offering plenary sessions, breakout sessions, and hot topics in a combined interprofessional format. This conference will discuss practice changing diagnostic and therapeutic changes in a wide range of clinical medicine.

Topics include:
Cancer in Iowa
AI and Medicine
Alzheimer's Updates
De...

College of Pharmacy PPS Guest Speaker:  Timothy Aungst, PharmD promotional image

College of Pharmacy PPS Guest Speaker: Timothy Aungst, PharmD

Thursday, October 1, 2026 12:30pm
College of Pharmacy Building

The Department of Pharmacy Practice and Science in the College of Pharmacy will host a guest speaker:

Timothy Aungst
Professor
Department of Pharmacy Practice
School of Pharmacy
Massachusetts College of Pharmacy and Health Sciences
Boston, MA

Seminar Title: "Teaching in the Age of AI Rethinking Learning, Assessment, and the Pharmacy Curriculum"

All are welcome to attend. No pre-registration required.