Welcome to CBB

The Center for Biocatalysis and Bioprocessing (CBB) is a microbial biomanufacturing and research facility that bridges the gap between laboratory discovery and commercial-scale bioprocessing solutions. Located at the University of Iowa, CBB offers microbial fermentation, recombinant protein expression, and downstream protein purification services for a wide variety of clients, including international corporations and early-stage start-up companies. For clients interested in clinical applications, a cGMP suite is available to manufacture of proteins under the quality standards defined by the U.S. Food and Drug Administration specifically for Phase 1 clinical trials.  

 

By combining the technical capabilities of a university-based pilot-scale CDMO with the expertise of affiliated faculty and researchers, the CBB serves as a trusted partner to biotech startups, vendors for the life science community, pharmaceutical companies, and academic innovators. Our facility supports innovation across multiple sectors, supporting the development and scale-up of protein-based therapeutics, specialty enzymes, reagent proteins, and other next-generation biologics. In addition, CBB plays a key role in bioprocessing workforce development through graduate training and NIH-funded biomanufacturing fellowships, thereby helping to shape the future of the biotech and life sciences industries.  

We Work with a Wide Range of Clients across the Biotech, Life Sciences, and Pharmaceutical Spaces

We welcome clients from diverse industry sectors, including biotech startups seeking scalable biomanufacturing, academic research laboratories advancing translational science, life science vendors supporting basic and applied research worldwide, as well as large multinational pharmaceutical manufacturers and government agencies involved in drug development and public health initiatives. Our services are accessible to clients regardless of geographic location, ensuring professional support for protein production, purification, and bioprocess development. 

How to Start a Service with CBB?

We’re here to support your project every step of the way. Getting started with the Center for Biocatalysis and Bioprocessing (CBB) is simple. Clients can request services by completing our Client Request Form online. After submitting the form, a CBB representative will contact you within 2-3 business days to confirm your request and to schedule an initial consultation.  

 

During this initial consultation, your project requirements will be discussed in a non-confidential manner. CBB will then evaluate whether our facility can meet your specific needs. If so, a Confidential Disclosure Agreement (CDA) template will be provided for your consideration. In parallel, we will share a ballpark estimate of the costs for your project.  
 
Upon execution of the CDA, a more in-depth discussion will be used to provide a more accurate assessment of the costs for CBB’s bioprocessing services. Services can begin once a Master Service Agreement is in place and a Project Ordered is created specifically tailored toward your bioprocessing needs.  
 
Our team will be with you through every step to ensure a smooth and compliant bioprocessing experience.  

Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience
CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students
CBB Operator Working in the Lab

55 +

Associated UI Faculty

News

Maria Spies, Ph.D.

Saturday, November 15, 2025

Tyler J. Woodward

Wednesday, October 15, 2025

Hossein Zare

Wednesday, October 15, 2025

Reza Nejadnik

Wednesday, October 15, 2025

Meet Some of Our Associated Faculty

Office of VP for Research Events

Application Deadline: Fall 2026 Obermann Writing Collective promotional image

Application Deadline: Fall 2026 Obermann Writing Collective

Thursday, August 27, 2026 5:00pm
111 Church Street

This program offers accountability to artists, scholars, and researchers working on any kind of writing project (articles, essays, fellowship or grant applications, dissertations, book projects, edited volumes, etc.) who want dedicated time, a cozy space, and a community for the practice of writing. Each group meets once a week for 1.5 hours in the Writers' Attic at the Obermann Center for Advanced Studies (111 Church St.). Weekly writing sessions include brief check-ins, goal setting, and...

Maximizing Pivot to Find Funding and Collaborators (August 2026) promotional image

Maximizing Pivot to Find Funding and Collaborators (August 2026)

Monday, August 31, 2026 1:00pm to 2:00pm
Virtual

Do you want to maximize your time spent searching for funding opportunities or potential project collaborators? Join us to learn how Pivot can save you time and effort in identifying the right funding opportunities for your research lines as well as identifying collaborators with the relevant expertise.

Register here. The RDO will send a calendar invitation and Zoom link upon registration.

College of Medicine Events

Iowa ReSpectacle Back to School Donation Drive promotional image

Iowa ReSpectacle Back to School Donation Drive

Wednesday, August 26 to Wednesday, September 2, 2026 (all day)
Medical Education Research Facility
Donate used glasses to be recycled and redistributed across the globe during the back-to-school season! Drop-off locations are available from Aug. 24 to Sept. 25 across the University of Iowa campuses and clinics.
Iowa ReSpectacle Back to School Donation Drive promotional image

Iowa ReSpectacle Back to School Donation Drive

Thursday, August 27 to Wednesday, September 2, 2026 (all day)
Medical Education Research Facility
Donate used glasses to be recycled and redistributed across the globe during the back-to-school season! Drop-off locations are available from Aug. 24 to Sept. 25 across the University of Iowa campuses and clinics.

College of Pharmacy Events

Progress 2026: Learning Together in the 21st Century promotional image

Progress 2026: Learning Together in the 21st Century

Thursday, October 1 to Friday, October 2, 2026 (all day)
Hyatt Regency Place

Overview:
Emphasizing the interprofessional team approach to patient care, the annual Progress conference combines internal medicine and pharmacy continuing education programs into a single multi-track program offering plenary sessions, breakout sessions, and hot topics in a combined interprofessional format. This conference will discuss practice changing diagnostic and therapeutic changes in a wide range of clinical medicine.

Topics include:
Cancer in Iowa
AI and Medicine
Alzheimer's Updates
De...

Progress 2026: Learning Together in the 21st Century promotional image

Progress 2026: Learning Together in the 21st Century

Friday, October 2, 2026 (all day)
Hyatt Regency Place

Overview:
Emphasizing the interprofessional team approach to patient care, the annual Progress conference combines internal medicine and pharmacy continuing education programs into a single multi-track program offering plenary sessions, breakout sessions, and hot topics in a combined interprofessional format. This conference will discuss practice changing diagnostic and therapeutic changes in a wide range of clinical medicine.

Topics include:
Cancer in Iowa
AI and Medicine
Alzheimer's Updates
De...