Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience

CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students

CBB Operator Working in the Lab

55 +

Associated UI Faculty

Microbial Manufacturing Services

As a microbial manufacturing & bioprocessing facility, our diverse team at the CBB specializes in cGMP and non-cGMP production of protein products for various business, commercial, and research purposes. We have years of experience in developing bioprocesses for scaling up fermentation & protein purification (including difficult to purified inclusion bodies), cGMP manufacturing, cell banking, instrumentation, and more. 

All critical equipment within the facility passed Factory Acceptance Tests (FAT), Installation Qualification (IQ), and Operational Qualification (OQ). This facility is open for audit by clients. 

With many successful campaigns over the years, the CBB has become a trusted partner for our local & international clients alike.

Request Services Now!

We have worked with clients ranging from large pharmaceutical companies to biotech startups of all sizes to virtual companies, academic research labs, and governmental agencies. Our facility produces protein-based products for all sorts of purposes, including Phase-1 clinical trials. The quality of all manufactured products are ensured by our dedicated QA/QC team. 

CBB Operator Working in the Lab

Non-cGMP Facility

Our non-cGMP Facility is fully equipped with advanced technologies & instruments to provide both upstream & downstream process development services to our clients, from strain development to large scale manufacturing. All projects are carried out by full-time staff with years of experience in research & process development. 

CBB Operator Working in the Lab

cGMP Facility

The cGMP Manufacturing Facility at CBB is capable of producing protein products for Phase-1 clinical trials. This cGMP Manufacturing Facility and the Non-cGMP Facility share similar equipment, allowing for efficient process transfer between the two facilities. Our facility strictly follows the 2008 FDA guidance for cGMP manufacturing of materials for Phase-1 investigational drugs. 

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

Educational & Training Opportunities

Every year, the CBB awards multiple fellowships to predoctoral student applicants to support their graduate research in the biocatalytic sciences (see definition). In addition to our own CBB fellowship program, the CBB also administers NIH fellowships. 

Both NIH and CBB fellowships are designed to promote training focusing on the applications of biological & physical sciences to conduct interdisciplinary research in all domains of biotechnology. 

Learn More About Our Fellowships

Most of our fellows have successfully entered the biotech job market right after graduation because they not only graduated with multiple journal publications, but also with industrial internship experience. 

Supportive Faculty Trainers

Our fellows are students working in a CBB-associated faculty's laboratory at The University of Iowa. Faculty help students obtain internships, build their work portfolios, and prepare job application materials. 

Predoctoral graduate students are encouraged to discuss with their major advisors as soon as possible regarding the application process. Students in their 1st and 2nd year are given priority.

Supporting Fellows Beyond Graduation

Once a CBB fellow, always a CBB fellow-From academic to personal to professional development, the CBB & our committed faculty provide continuous guidance & mentorship to our fellows even after their graduation.

 

"Center of Biocatalysis and Bioprocessing was very generous to award to me a 2-year Pre-Doctoral Fellowship in biotechnology for my PhD at UIOWA. Furthermore, I had a great opportunity of visit CBB facility and learn about protein purification services for Phase 1 clinical trial and downstream purification and bioprocessing."

Meet Some of Our Associated Faculty

Office of VP for Research Events

Summer 2024 Office Hours

Wednesday, July 31, 2024 2:00pm to 4:00pm
Virtual
Office Hours: IRB Office Hours are for all UI faculty, staff, and Investigators, HawkIRB delegates, and research team members involved with Human Subjects research. No appointment necessary. First come, first served; HSO Staff will be available to: Answer questions about conducting human subjects research. Provide guidance and answer questions about the electronic application forms in the HawkIRB system. Provide suggestions and guidance about study procedures that are in compliance with federal regulations and the UI IRB policies. Provide guidance and answer questions about the submission of industry-initiated and industry-sponsored research projects to Western IRB (WIRB).
Art & Write Night promotional image

Art & Write Night

Friday, August 2, 2024 6:00pm to 8:00pm
University of Iowa Museum of Natural History
Join the long, rich, historical tradition of artists creating in our spaces. Professional, aspiring, and amateur artists alike, make our museum your muse. The return of this popular program series welcomes guests into the Museum of Natural History's magical gallery spaces after-hours to work on sketching or writing projects with other campus and community artists. Tell a friend, grab a notebook, and join us on the first Friday of each month. We'll provide a new inspo prompt for each session...

College of Medicine Events

IHDR Summer Seminar Series

Thursday, August 1, 2024 11:00am to 12:00pm
Virtual
Please join us every Thursday throughout the summer for this exciting seminar series! Each week a different expert will present on topics geared to enhance your understanding and accessibility of health science data.  Seminars will take place over Zoom 11 a.m.–noon CST.

Biochemistry and Molecular Biology Seminar: Dr. Yikang Rong (Univ of South China)

Monday, August 5, 2024 1:30pm to 2:20pm
Medical Education Research Facility
"A Tale of Two snRNAs" Yikang Rong, PhD Professor, Hengyang College of Medicine University of South China

College of Pharmacy Events

2024 College of Pharmacy White Coat Ceremony promotional image

2024 College of Pharmacy White Coat Ceremony

Saturday, August 24, 2024 10:00am to 11:30am
Hancher Auditorium
The College of Pharmacy will host a special ceremony to welcome the Class of 2028 into the pharmacy profession and college family on Aug. 24. This event is sponsored by Walgreens.
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Study Abroad Fair

Tuesday, September 17, 2024 11:00am to 3:00pm
Iowa Memorial Union (IMU)
Get your questions answered and kick-start your global experience at the University of Iowa fall Study Abroad Fair!